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Powering Precision Health 

with InformedDNA

Laboratory
Result Analysis & 

Interpretation Services

Our Results Analysis & Interpretation Engine gives laboratories

the ability to enhance results with robust genomic insights
essential for truly personalized care.

Genotype Analyses
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Labs
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We empower health organizations, research institutions, and diagnostic providers with cutting-edge pharmacogenomics (PGx) testing and infectious disease molecular diagnostics. Backed by decades of scientific expertise and curated genomic literature, we provide scientifically-rigorous and informative reports designed, to enhance diagnostic accuracy and support effective therapeutic decision-making.

Offerings Include:

Pharmacogenomics (PGx)

Leveraging sophisticated algorithms, our PGx solution analyzes clinical laboratory pharmacogenomic results to interpret how an individual’s unique genetic makeup influences their response to medications, in concert with other medication-associated risks. This empowers your clients to tailor prescribing for improved safety and efficacy, potentially reducing adverse drug reactions and treatment waste.

GeneDose: Comprehensive Polypharmacy
Borne from the personalized medicine research study at the Coriell Institute for Medical Research where the landmark, peer-reviewed PhAESIS process1 for evidence evaluation was created, our GeneDose PGx provides comprehensive, clinically-relevant, and scientifically-rigorous results for pharmacogenomic and medication safety reporting.
  • We perform a meta-analysis of the available research literature using a process of evidence assessment that has been published and peer-reviewed. The ultimate findings of that meta-analysis are presented for consideration as the professional opinion of the research team.
  • Laboratories and other users may opt to create a research analysis of specific gene variations. The variations are aligned to the meta-analysis results for each gene:drug pairing. The resulting research analysis is distinct from the CLIA reporting of genetic variations from the laboratory. It exists as a 3rd party literature review from professional researchers. The analysis is not intended to provide clinical reporting, but rather to quickly surface relevant medical reference information that may be educational for its users.

Recommendations for, and against, specific ADHD medications based on the patient’s DNA.

Comprehensive analysis of risks associated with polypharmacy in the cardiac patient include drug-drug interactions, anticholinergic burden, age- and pregnancy-related concerns, FDA warnings, food and drink interactions, and genetics.

Based on an individual’s pharmacogenomics profile, this report provides details for the treatment of depression, anxiety, ADHD, and other psychiatric health concerns.

Addressing clinical pain management, CLS tackles medication safety, efficacy, and Opioid Use Disorder predilection in an actionable report that determines the most appropriate pain medication based on an individual’s DNA.

Details the diagnosis and lists medications to avoid. Available alone or as part of the Perioperative Medication Appropriateness Report.

Specialized Molecular Diagnostics

Includes interpretation of semi-quantitative laboratory assays of pathogenic microorganisms and, in concert with antibiotic resistance testing, provides antibiotic treatment options.

Women’s Health Interpretation and Reporting
Provides differential diagnoses of Bacterial Vaginosis (BV), Yeast Infection, and Trichomoniasis (Trich) Infections with increased specificity and sensitivity2,3. Treatment options based on diagnosis, history of recurrence, and pregnancy status are included to assist in rapid prescription decision making. This report can also include Aerobic Vaginitis (AV) and Sexually Transmitted Infections (STIs).

Enhances diagnostic accuracy and supports effective therapeutic decision-making for conditions such as gastroenteritis, food poisoning, and other GI-related ailments.

Provides identification of pathogenic organisms to guide rapid therapeutic decisions.

Diagnoses multiple respiratory ailments including SARS, pneumonia, and TB from a single sample.

Evaluates and provides insights on hard-to-manage wounds prevalent among elderly and diabetic patients.
Identifies a variety of dermatological and systemic fungal infections.

Provides detailed infection confirmation to guide rapid therapeutic decisions.

Why Partner with InformedDNA?

Gain access to the foundational insights required to drive personalized healthcare, optimize patient outcomes, and 
contribute to a healthier world.

All guidance is transparent and cited with the published literature references available for independent review. The literature research analysis also makes clear that the state of knowledge in pharmacogenomics is not fixed. New literature that refines previously published guidance, or provides wholly new guidance, is published continually. Researchers and other users who utilize PGx reference information, including any meta-analysis information generated by RAISE, should do so with the full knowledge of these limitations.

1. The Coriell Personalized Medicine Collaborative Pharmacogenomics Appraisal, Evidence Scoring and Interpretation System, Genome Medicine, October 2013. Gharani, N; Keller, MA; Stack, CB; Hodges, LM; Schmidlen, TJ; Lynch, DE; Gordon, ES; Christman, MF.

2. Diagnosing Bacterial Vaginosis with a Novel, Clinically-Actionable Molecular Diagnostic Tool. J Appl Microb Res. Vol: 1, Issue: 2 (01-08). Jarvis JP, Rains D, Kradel SJ, Elliott J, Diamond EE, Avaniss-Aghajani E, Yasharpour F, Shaman JA (2018)

3. https://pubmed.ncbi.nlm.nih.gov/31315951/

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